Colief Infant Drops



About Colief®

Colief® Infant Drops is the original lactase enzyme and has been on the market over 15 years.  Trusted by mums and recommended by healthcare professionals Colief® Infant Drops is the number one prescribed colic remedy  and the only product supported by clinical studies. Colief® Infant Drops is formulated to provide reassuring relief for the symptoms of colic caused by temporary lactose intolerance. Colief® contains lactase, an enzyme naturally occurring in our bodies that helps break down complex sugar lactose found in milk, dairy products, breast milk and infant formulas.
The immature digestive system of babies can have trouble breaking down lactose into more simple sugars causing discomfort commonly known as colic and characterised by lengthy periods of distressed crying in an infant aged under four months. The technical name for this is Temporary Lactase Deficiency. Colief® Infant Drops can help the body break down the lactose into simpler sugars, glucose and galactose, making it easier for your baby to digest their feeds.
The drops can be used every time you feed your baby. At around three to four months old a baby's digestive system will naturally cope better with lactose and usually symptoms will disappear. However, if symptoms persist you can continue to use Colief® Infant Drops. Colief contains an enzyme which is destroyed by heat so for best results use Colief between room temperature and body-heat, which is neither too hot nor too cold. Always follow the manufacturer's instructions carefully when making-up formula milk.
If your baby's crying persists or if you have any concerns regarding your baby's health or wellbeing, you should seek professional medical advice without delay.

The Colief® Story

Colief® Infant Drops are the result of a desperate mother, searching for a solution to her baby’s constant crying. She turned to her GP for help with her baby. They felt that the cause of the baby's problems was linked to lactase enzyme deficiency and the GP remembered seeing a product containing lactase enzyme on sale in the USA. When added to milk, it allowed people with lactase deficiency to consume milk or dairy products without unpleasant side effects.
It occurred to the mother that this lactase enzyme product could be specially formulated for babies with Temporary Lactase Deficiency. Initial hospital trials in Cork showed that the product had a pronounced effect on babies with Temporary Lactase Deficiency. The trial was small but the results were significant and were published in the Journal of Human Nutrition and Dietetics in September 1998. They showed that by breaking down most of the lactose in a baby’s feed by adding lactase enzyme drops to the milk a number of hours before feeding, the hours of crying were significantly reduced. These results were confirmed by a subsequent, larger trial at Guys Hospital in London, published in October 2001.
So what started as one mother’s determined search for the answer to her daughter’s suffering has resulted in the development of a product, which has the potential to improve the quality of life of numerous babies and their parents.

Colief® as a Diagnostic

As any parent with a distressed, crying baby knows, colic affects a whole household, and can be very frustrating and upsetting for parents. Colic is defined as repeated episodes of excessive and inconsolable crying in a newborn baby which otherwise appears to be perfectly healthy. The condition affects up to 1 in 5 babies.
Research has found that Temporary Lactase Deficiency is an important factor for many babies with colic. A lack of lactase enzyme in the small intestine results in a baby's inability to fully digest the milk-sugar lactose. The undigested lactose is then broken down in the bowel, producing lactic acid and hydrogen gas. This leads to discomfort, bloating and wind.
A one-week trial of Colief® Infant Drops can help a parent identify if Temporary Lactase Deficiency is the cause of their baby's colic symptoms. If the baby shows no signs of improvement after a week, it can be ruled out as the cause and other possible causes can then be investigated. Temporary Lactase Deficiency does not put a baby's health at risk and will normally resolve itself around four months.

Usage instructions

When breastfeeding:
  • Try expressing a few drops of breast milk into a small sterilized container.
  • Add 4 drops of Colief
  • Give this to your baby on a sterilized, plastic teaspoon
  • Continue breast feeding as normal
Using Colief with Infant Formula:
  • Carefully prepare your baby’s feed according to the manufacturer’s instructions
  • Add 4 drops of Colief to formula that is warm taking care that it is not hot.
  • Shake occasionally and feed the baby after half an hour having checked that the bottle is at the correct feeding temperature
  • Discard any unused feed

If you need to make up your baby’s feed in advance:
  • Carefully prepare your baby’s meal according to the manufacturer’s instructions
  • Add 2 drops of Colief to warm milk and store in the refrigerator for 4 hours then use within 12 hours from the time of preparation.
  • Warm at feeding temperature and feed as normal
  • Discard any unused feed
For more information please visit or την  
Diagnosing Colic
What is Colic
What is Colief
How to use Colief with infant formula
How to cope with a colicky baby
When should I see a doctor
How to use Colief when breastfeeding
How to withdraw Colief from use